KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC6L
All Species:
16.36
Human Site:
Y696
Identified Species:
51.43
UniProt:
Q2NKX8
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2NKX8
NP_060139.2
1250
141103
Y696
D
V
V
E
E
S
H
Y
I
Q
Q
R
V
Q
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092609
1252
141491
Y696
D
V
V
E
E
S
H
Y
I
Q
Q
R
V
Q
K
Dog
Lupus familis
XP_549075
1268
143171
Y720
D
V
I
E
E
S
H
Y
I
Q
Q
R
V
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHK9
1240
138836
Y699
D
M
L
E
D
S
Q
Y
I
H
Q
R
V
Q
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505482
1393
155753
Y699
Q
E
M
E
E
R
R
Y
I
Q
Q
R
V
Q
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2BGR3
1451
163208
H711
P
E
D
A
E
S
H
H
Y
I
Q
T
R
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P41877
1009
116656
N492
T
P
H
E
D
R
S
N
A
I
E
A
Y
N
A
Sea Urchin
Strong. purpuratus
XP_781405
563
63991
A46
L
D
I
L
Q
K
A
A
K
I
Q
K
T
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.5
78.8
N.A.
73.4
N.A.
N.A.
49.9
N.A.
N.A.
44.4
N.A.
N.A.
N.A.
24.7
22.9
Protein Similarity:
100
N.A.
98.4
85.8
N.A.
82.3
N.A.
N.A.
63.8
N.A.
N.A.
60
N.A.
N.A.
N.A.
42.7
33.2
P-Site Identity:
100
N.A.
100
93.3
N.A.
66.6
N.A.
N.A.
66.6
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
86.6
N.A.
N.A.
73.3
N.A.
N.A.
40
N.A.
N.A.
N.A.
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
0
13
13
13
0
0
13
0
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
13
13
0
25
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
25
0
75
63
0
0
0
0
0
13
0
0
13
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
13
0
0
0
50
13
0
13
0
0
0
0
0
% H
% Ile:
0
0
25
0
0
0
0
0
63
38
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
13
0
0
13
0
0
13
0
0
75
% K
% Leu:
13
0
13
13
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
13
13
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
13
0
0
0
0
0
13
0
% N
% Pro:
13
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
13
0
0
0
13
0
13
0
0
50
88
0
0
63
13
% Q
% Arg:
0
0
0
0
0
25
13
0
0
0
0
63
13
0
0
% R
% Ser:
0
0
0
0
0
63
13
0
0
0
0
0
0
0
0
% S
% Thr:
13
0
0
0
0
0
0
0
0
0
0
13
13
0
0
% T
% Val:
0
38
25
0
0
0
0
0
0
0
0
0
63
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
63
13
0
0
0
13
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _